Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | PDE4A | P27815 | 2/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25773363 | 0.90 | TSHR (0.56) | TSHRMAPK1MAPTCYP3A4TDP1 | |
| SCHEMBL11967263 | 0.90 | TSHR (0.66) | TSHRMAPK1MAPTCYP3A4TDP1 | |
| SCHEMBL31619806 | 0.90 | TSHR (0.66) | TSHRMAPK1MAPTCYP3A4TDP1 | |
| SCHEMBL5113232 | 0.90 | TSHR (0.66) | TSHRMAPK1MAPTCYP3A4TDP1 | |
| SCHEMBL5113231 | 0.90 | TSHR (0.66) | TSHRMAPK1MAPTCYP3A4TDP1 | |
| SCHEMBL31632614 | 0.86 | TSHR (0.59) | TSHRMAPK1MAPTCYP3A4TDP1 | |
| SCHEMBL31620968 | 0.86 | TSHR (0.59) | TSHRMAPK1MAPTCYP3A4TDP1 | |
| SCHEMBL25773302 | 0.85 | MAPK1 (0.53) | TSHRMAPK1MAPTCYP3A4TDP1 | |
| SCHEMBL31620981 | 0.84 | TSHR (0.56) | TSHRMAPK1MAPTCYP3A4TDP1 | |
| SCHEMBL31620970 | 0.84 | TSHR (0.53) | TSHRMAPK1MAPTCYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109802-A1 | TRICYCLIC FUSED HETEROCYCLIC PDE3/4 DUAL INHIBITOR AND USE THEREOF | 海思科医药集团股份有限公司 | 2023-06-22 | — | — | WO | disclosed |