Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.59 |
| ▸ | OSBP | P22059 | 4/20 | 0.59 |
| ▸ | USP2 | O75604 | 3/20 | 0.59 |
| ▸ | OSBP2 | Q969R2 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | RORA | P35398 | 3/20 | 0.54 |
| ▸ | NPC1L1 | Q9UHC9 | 3/20 | 0.54 |
| ▸ | GPR183 | P32249 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.49 |
| ▸ | CRYAB | P02511 | 1/20 | 0.47 |
| ▸ | HMGCR | P04035 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6119630 | 1.00 | RORC (0.59) | RORCOSBPUSP2OSBP2LMNA | |
| SCHEMBL18714203 | 0.89 | RORC (0.62) | RORCOSBPUSP2OSBP2LMNA | |
| SCHEMBL18714205 | 0.89 | RORC (0.62) | RORCOSBPUSP2OSBP2LMNA | |
| SCHEMBL13966714 | 0.89 | RORC (0.62) | RORCOSBPUSP2OSBP2LMNA | |
| SCHEMBL23368414 | 0.86 | GRIN1 (0.46) | RORCOSBPUSP2OSBP2LMNA | |
| SCHEMBL27322122 | 0.84 | RORC (0.56) | RORCOSBPUSP2OSBP2LMNA | |
| SCHEMBL27252463 | 0.84 | RORC (0.56) | RORCOSBPUSP2OSBP2LMNA | |
| SCHEMBL27859651 | 0.83 | RORC (0.55) | RORCOSBPUSP2OSBP2LMNA | |
| SCHEMBL25911439 | 0.81 | NR1H3 (0.44) | RORCOSBPUSP2OSBP2LMNA | |
| SCHEMBL23776993 | 0.78 | GRIN1 (0.41) | RORCOSBPUSP2OSBP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023126404-A1 | LIPID-BASED FORMULATIONS FOR ADMINISTRATION OF RNA | BioNTech SE (DE) | 2023-07-06 | — | — | WO | disclosed |
| WO-2023126053-A1 | LIPID-BASED FORMULATIONS FOR ADMINISTRATION OF RNA | BioNTech SE (DE) | 2023-07-06 | — | — | WO | disclosed |