SCHEMBL25775375

SCHEMBL25775375

c1ccc(-c2cccc(-n3c4ccccc4c4cc5c(cc43)c3ccccc3n5-c3cccc4c3sc3ccccc34)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.40
KDM4E B2RXH2 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
TNKS O95271 1/20 0.37
TNKS2 Q9H2K2 1/20 0.37
ALOX5 P09917 1/20 0.37
MAPT P10636 2/20 0.34
RXFP1 Q9HBX9 1/20 0.34
ALDH1A1 P00352 2/20 0.33
TP53 P04637 1/20 0.32
PRKDC P78527 1/20 0.31
HSD17B10 Q99714 1/20 0.31
FAAH O00519 1/20 0.31
HSP90AA1 P07900 1/20 0.31
PKM P14618 1/20 0.31
HTT P42858 1/20 0.31
MGLL Q99685 1/20 0.31
PMM2 O15305 1/20 0.30
IDE P14735 1/20 0.30
MPI P34949 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23072371 0.99 ALOX5 (0.39) ATMKDM4EL3MBTL1TNKSTNKS2
SCHEMBL26705050 0.96 ATM (0.39) ATMKDM4EL3MBTL1TNKSTNKS2
SCHEMBL25615792 0.95 ALOX5 (0.38) ATMKDM4EL3MBTL1TNKSTNKS2
SCHEMBL21481276 0.94 ALOX5 (0.39) ATMKDM4EL3MBTL1TNKSTNKS2
SCHEMBL25941314 0.94 ALOX5 (0.39) ATMKDM4EL3MBTL1TNKSTNKS2
SCHEMBL16641487 0.94 ALOX5 (0.39) ATMKDM4EL3MBTL1TNKSTNKS2
SCHEMBL24230728 0.93 ALOX5 (0.37) ATMKDM4EL3MBTL1TNKSTNKS2
SCHEMBL19009389 0.93 ALOX5 (0.38) ATMKDM4EL3MBTL1TNKSTNKS2
SCHEMBL19009378 0.93 ALOX5 (0.38) ATMKDM4EL3MBTL1TNKSTNKS2
SCHEMBL24915246 0.92 KDM4E (0.33) ATMKDM4EL3MBTL1TNKSTNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4266390-A1 ORGANIC LIGHT EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-10-25 EP disclosed
US-20230200227-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-06-22 US disclosed
US-20230200227-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-06-22 US disclosed