SCHEMBL25779233

SCHEMBL25779233

N#Cc1ccc(-c2sncc2C(=O)O)nc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRS3 P32247 1/20 0.38
GRM5 P41594 3/20 0.36
EGLN2 Q96KS0 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SLC22A12 Q96S37 3/20 0.35
SCD5 Q86SK9 1/20 0.35
JAK2 O60674 1/20 0.35
PARP1 P09874 1/20 0.34
PARP2 Q9UGN5 1/20 0.34
XDH P47989 1/20 0.34
P4HA1 P13674 1/20 0.34
P4HTM Q9NXG6 1/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
HTT P42858 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
KDM4C Q9H3R0 1/20 0.34
TMPRSS4 Q9NRS4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25779225 0.81 EGLN2 (0.34) BRS3EGLN2MEN1KMT2ASLC22A12
SCHEMBL25779230 0.81 SLC22A12 (0.43) BRS3SLC22A12PARP1XDH
SCHEMBL25778943 0.77 KDM4C (0.36) BRS3GRM5EGLN2MEN1KMT2A
SCHEMBL25779234 0.76 KMO (0.38) XDHKDM4E
SCHEMBL25779102 0.74 KDM4E (0.49) GRM5EGLN2MEN1KMT2ASLC22A12
SCHEMBL25778912 0.74 GRM5 (0.39) BRS3GRM5EGLN2MEN1KMT2A
SCHEMBL25779267 0.73 PPARG (0.37) GRM5EGLN2MEN1KMT2ASLC22A12
SCHEMBL25779264 0.73 SLC22A12 (0.55) SLC22A12XDHHTT
SCHEMBL25779228 0.73 KDM4E (0.47) MEN1KMT2AP4HTMKDM4EALDH1A1
SCHEMBL25778938 0.70 GRM5 (0.38) BRS3GRM5EGLN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023118434-A1 PESTICIDALLY ACTIVE AMIDE COMPOUNDS GLOBACHEM NV (BE) 2023-06-29 WO disclosed