Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 7/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15110304 | 0.86 | KMT2A (0.61) | PLA2G4BSMPD1KMT2ATHRATHRB | |
| SCHEMBL30856532 | 0.86 | KMT2A (0.61) | PLA2G4BSMPD1KMT2ATHRATHRB | |
| SCHEMBL203967 | 0.86 | PARP1 (0.55) | PRSS1PARP1PLA2G4BSMPD1KMT2A | |
| SCHEMBL202662 | 0.84 | PRSS1 (0.52) | PRSS1PARP1PLA2G4BSMPD1KMT2A | |
| SCHEMBL20230313 | 0.83 | KMT2A (0.52) | KMT2A | |
| SCHEMBL20230319 | 0.83 | KMT2A (0.52) | KMT2A | |
| SCHEMBL5047908 | 0.83 | PARP1 (0.54) | PARP1PLA2G4BKMT2A | |
| SCHEMBL2183003 | 0.81 | SMPD1 (0.49) | PRSS1PLA2G4BSMPD1KMT2ATHRA | |
| SCHEMBL2183818 | 0.81 | SMPD1 (0.49) | PRSS1PLA2G4BSMPD1KMT2ATHRA | |
| SCHEMBL1387170 | 0.81 | PRSS1 (0.62) | PRSS1PARP1SMPD1KMT2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3548492-B1 | CELL IMPERMEABLE COELENTERAZINE ANALOGUES | PROMEGA CORP (US) | 2023-07-05 | — | — | EP | disclosed |