Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15110304 | 1.00 | KMT2A (0.61) | KMT2APLA2G4BNR4A2NR4A1NR4A3 | |
| SCHEMBL15110387 | 0.88 | KMT2A (0.57) | KMT2APLA2G4BNR4A2NR4A1NR4A3 | |
| SCHEMBL30856531 | 0.88 | KMT2A (0.57) | KMT2APLA2G4BNR4A2NR4A1NR4A3 | |
| SCHEMBL16923977 | 0.88 | KMT2A (0.57) | KMT2APLA2G4BNR4A2NR4A1NR4A3 | |
| SCHEMBL15110547 | 0.87 | ALDH1A1 (0.55) | KMT2ASMN1; SMN2SMPD1POLBNPC1 | |
| SCHEMBL25780554 | 0.86 | PRSS1 (0.51) | KMT2APLA2G4BSMPD1THRATHRB | |
| SCHEMBL1928759 | 0.85 | KMT2A (0.57) | KMT2APLA2G4BNR4A2NR4A1NR4A3 | |
| SCHEMBL21577271 | 0.85 | CHRNB2 (0.51) | SMN1; SMN2 | |
| SCHEMBL16673260 | 0.84 | L3MBTL1 (0.52) | KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL13986556 | 0.83 | SMN1; SMN2 (0.58) | KMT2ASMN1; SMN2POLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736134-A | Compounds and methods for enhancing degradation of target proteins and other polypeptides by E3 ubiquitin ligases | 耶鲁大学 | 2024-03-22 | — | — | CN | disclosed |