Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25782151 | 0.81 | ALOX5AP (0.44) | ALOX5APFEN1F2RL3GPR119 | |
| SCHEMBL25283904 | 0.80 | P2RX7 (0.43) | ALOX5APFEN1F2RL3 | |
| SCHEMBL31140673 | 0.80 | P2RX7 (0.43) | ALOX5APFEN1F2RL3 | |
| SCHEMBL25245465 | 0.80 | P2RX7 (0.43) | ALOX5APFEN1F2RL3 | |
| SCHEMBL25241164 | 0.80 | ALOX5AP (0.39) | ALOX5APFEN1F2RL3CHEK2BRD4 | |
| SCHEMBL30478920 | 0.80 | ALOX5AP (0.39) | ALOX5APFEN1F2RL3CHEK2BRD4 | |
| SCHEMBL25285009 | 0.80 | ALOX5AP (0.39) | ALOX5APFEN1F2RL3CHEK2BRD4 | |
| SCHEMBL30478878 | 0.79 | ALOX5AP (0.38) | ALOX5APFEN1F2RL3BRD4IRAK4 | |
| SCHEMBL25236708 | 0.79 | ALOX5AP (0.38) | ALOX5APFEN1F2RL3BRD4IRAK4 | |
| SCHEMBL25283402 | 0.79 | ALOX5AP (0.38) | ALOX5APFEN1F2RL3BRD4IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116779-A1 | DIALKYNE COMPOUND AND USE THEREOF | 上海艾力斯医药科技股份有限公司 | 2023-06-29 | — | — | WO | disclosed |