Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25782746 | 0.86 | PDE3B (0.46) | PDE3BPDE3AALOX5KMT2ASMN1; SMN2 | |
| SCHEMBL25782959 | 0.79 | KMT2A (0.46) | PDE3BPDE3AALOX5KMT2ASMN1; SMN2 | |
| SCHEMBL25782745 | 0.72 | EPHX2 (0.47) | MAOBALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL19555403 | 0.71 | MAOB (0.49) | PDE3BPDE3AALOX5KMT2ASMN1; SMN2 | |
| SCHEMBL20379000 | 0.70 | MAOB (0.50) | ALOX5MAOB | |
| SCHEMBL8880826 | 0.69 | CYP3A4 (0.53) | KMT2AMAOB | |
| SCHEMBL25782743 | 0.69 | THRA (0.53) | KMT2ASMN1; SMN2MAOBALDH1A1 | |
| SCHEMBL1097733 | 0.68 | MAOB (0.53) | PDE3BPDE3AKMT2ASMN1; SMN2MAOB | |
| SCHEMBL23732254 | 0.68 | KDM4E (0.55) | KMT2AALDH1A1MEN1LMNAMAPT | |
| SCHEMBL27045093 | 0.68 | CYP3A4 (0.55) | ALOX5MAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023115203-A1 | OXER1 ANTAGONISTS AND USES THEREOF | FAIRHAVEN PHARMACEUTICALS INC. (CA) | 2023-06-29 | — | — | WO | disclosed |