Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 4/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25783145 | 0.96 | PIN1 (0.46) | PIN1SLC6A2SLC6A4PDK2TSHR | |
| SCHEMBL25783124 | 0.88 | PIN1 (0.43) | PIN1SLC6A2SLC6A4TSHRSMN1; SMN2 | |
| SCHEMBL25783139 | 0.84 | TSHR (0.47) | PIN1SLC6A2SLC6A4TSHRSMN1; SMN2 | |
| SCHEMBL25783089 | 0.83 | PIN1 (0.50) | PIN1SLC6A2SLC6A4TSHRSMN1; SMN2 | |
| SCHEMBL29519632 | 0.83 | PIN1 (0.46) | PIN1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL19694905 | 0.83 | PIN1 (0.46) | PIN1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL25783130 | 0.82 | PDK2 (0.42) | PIN1SLC6A2SLC6A4PDK2TRPM8 | |
| SCHEMBL23529631 | 0.79 | PIN1 (0.42) | PIN1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL25783220 | 0.79 | TSHR (0.65) | PIN1SLC6A2SLC6A4PDK2TSHR | |
| SCHEMBL25783146 | 0.78 | PDK2 (0.41) | PIN1SLC6A2SLC6A4PDK2TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125928-A1 | MENIN INHIBITOR AND USE THEREOF | 成都先导药物开发股份有限公司 | 2023-07-06 | — | — | WO | disclosed |