Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25772437 | 0.85 | S1PR1 (0.38) | S1PR1S1PR5NOTUMCYP4F2CYP4A11 | |
| SCHEMBL25783157 | 0.85 | S1PR1 (0.39) | S1PR1S1PR5NOTUMCYP4F2CYP4A11 | |
| SCHEMBL25782854 | 0.84 | S1PR1 (0.40) | S1PR1S1PR5RAB9ABCHENOTUM | |
| SCHEMBL25772309 | 0.83 | MEN1 (0.39) | S1PR1S1PR5NOTUMCYP4F2CYP4A11 | |
| SCHEMBL25783158 | 0.79 | S1PR1 (0.40) | S1PR1S1PR5NOTUMCYP4F2CYP4A11 | |
| SCHEMBL25772077 | 0.79 | OXER1 (0.47) | — | |
| SCHEMBL25772492 | 0.78 | MGLL (0.37) | S1PR1S1PR5CYP4F2CYP4A11LMNA | |
| SCHEMBL25772307 | 0.77 | CYP4F2 (0.37) | S1PR1S1PR5NOTUMCYP4F2CYP4A11 | |
| SCHEMBL25775002 | 0.77 | CYP4F2 (0.39) | S1PR1S1PR5NOTUMCYP4F2CYP4A11 | |
| SCHEMBL25782852 | 0.76 | TSHR (0.38) | TSHRCCR5LMNAMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023115203-A1 | OXER1 ANTAGONISTS AND USES THEREOF | FAIRHAVEN PHARMACEUTICALS INC. (CA) | 2023-06-29 | — | — | WO | disclosed |