Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23529631 | 0.86 | PIN1 (0.42) | PIN1KDM4EARMEN1KMT2A | |
| SCHEMBL25598466 | 0.85 | KDM4E (0.43) | PIN1KDM4EALDH1A1TSHRAR | |
| SCHEMBL25598182 | 0.85 | KDM4E (0.43) | PIN1KDM4EALDH1A1TSHRAR | |
| SCHEMBL25783124 | 0.81 | PIN1 (0.43) | PIN1KDM4EALDH1A1TSHRMEN1 | |
| SCHEMBL25783139 | 0.80 | TSHR (0.47) | PIN1KDM4EALDH1A1TSHRMEN1 | |
| SCHEMBL29932506 | 0.80 | KDM4E (0.48) | PIN1KDM4EALDH1A1TSHRAR | |
| SCHEMBL30440324 | 0.80 | KDM4E (0.48) | PIN1KDM4EALDH1A1TSHRAR | |
| SCHEMBL23529573 | 0.80 | KDM4E (0.48) | PIN1KDM4EALDH1A1TSHRAR | |
| SCHEMBL24476967 | 0.79 | KDM4E (0.50) | PIN1KDM4EALDH1A1TSHRAR | |
| SCHEMBL19694905 | 0.79 | PIN1 (0.46) | PIN1KDM4EARMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125928-A1 | MENIN INHIBITOR AND USE THEREOF | 成都先导药物开发股份有限公司 | 2023-07-06 | — | — | WO | disclosed |