Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | IKBKB | O14920 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 7/20 | 0.37 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3809376 | 0.75 | HTR2C (0.59) | HTR2CIKBKBPARP1CHUKHTR6 | |
| Hydrochloric Acid SCHEMBL27587929 | 0.74 | HTR2C (0.60) | HTR2CIKBKBPARP1CHUKHTR6 | |
| SCHEMBL27725541 | 0.73 | PLAT (0.43) | HTR2CHTR6SLC6A2SLC6A4 | |
| SCHEMBL4297429 | 0.72 | SLC6A2 (0.46) | HTR2CIKBKBHTR6HTR1ASLC6A2 | |
| SCHEMBL167910 | 0.72 | PARP1 (0.45) | HTR2CIKBKBPARP1CHUKHTR1A | |
| SCHEMBL6783764 | 0.70 | SLC6A4 (0.44) | HTR2CIKBKBHTR6HTR1ASLC6A2 | |
| SCHEMBL16717673 | 0.68 | BRD4 (0.37) | — | |
| SCHEMBL17004903 | 0.68 | BRD4 (0.37) | — | |
| SCHEMBL28744208 | 0.68 | MAPT (0.38) | IKBKBSLC6A3 | |
| SCHEMBL15566704 | 0.68 | MAP3K5 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114931-B1 | PIPERIDINE GPCR AGONISTS | PROSIDION LTD (GB) | 2011-11-02 | — | — | EP | disclosed |