Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30798310 | 0.81 | HTR2C (0.43) | PLATHTR2CHTR6TSHRGAA | |
| SCHEMBL24718025 | 0.81 | HTR2C (0.43) | PLATHTR2CHTR6TSHRGAA | |
| SCHEMBL3676421 | 0.78 | TSHR (0.56) | PLATHTR2CTSHRALDH1A1HSD17B10 | |
| SCHEMBL5584483 | 0.75 | HTR2C (0.60) | HTR2CHTR6SLC6A2SLC6A4 | |
| SCHEMBL5362021 | 0.74 | CA12 (0.46) | TSHRGAAALOX15KDM4EALDH1A1 | |
| SCHEMBL2578334 | 0.73 | HTR2C (0.39) | HTR2CHTR6SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL28470155 | 0.73 | CA12 (0.47) | PLATHTR2CALOX15KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL30736680 | 0.72 | HTR2C (0.46) | PLATHTR2CHTR6KDM4E | |
| SCHEMBL7437362 | 0.72 | LMNA (0.55) | TSHRGAALMNA | |
| SCHEMBL29003855 | 0.72 | HTR2C (0.51) | HTR2CHTR6SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101321726-A | Novel fused pyrrole derivative | DAINIPPON SUMITOMO PHARMA CO (JP) | 2008-12-10 | — | — | CN | disclosed |