Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | PPARG | P37231 | 6/20 | 0.47 |
| ▸ | PPARD | Q03181 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Serine SCHEMBL2578606 | 1.00 | KMT2A (0.52) | KMT2ASOAT1MEN1FAAHTP53 | |
| Palmitic Acid SCHEMBL28927197 | 0.89 | GPR84 (0.63) | KMT2AMEN1CYP1A2CYP2C19ALOX15 | |
| Octanoic Acid SCHEMBL26624656 | 0.89 | GPR84 (0.63) | KMT2AMEN1CYP1A2CYP2C19ALOX15 | |
| Myristic Acid SCHEMBL27890892 | 0.89 | GPR84 (0.63) | KMT2AMEN1CYP1A2CYP2C19ALOX15 | |
| Decanoic Acid SCHEMBL13279587 | 0.89 | GPR84 (0.63) | KMT2AMEN1CYP1A2CYP2C19ALOX15 | |
| Dodecanoate SCHEMBL25310996 | 0.89 | GPR84 (0.63) | KMT2AMEN1CYP1A2CYP2C19ALOX15 | |
| Glutamine SCHEMBL28234616 | 0.85 | KMT2A (0.70) | KMT2ASOAT1MEN1FAAHTP53 | |
| Dodecanol SCHEMBL30392850 | 0.85 | GRIK1 (0.53) | KMT2AMEN1GRIK1GRIK2NOD1 | |
| Cetostearyl Alcohol SCHEMBL27937331 | 0.85 | GRIK1 (0.53) | KMT2AMEN1GRIK1GRIK2NOD1 | |
| Decanoic Acid SCHEMBL29031179 | 0.84 | CA1 (0.52) | GRIK1GRIK2NOD1GPR84FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2384118-A1 | SPHINGO-GUANIDINES AND THEIR USE AS INHIBITORS OF SPHINGOSINE KINASE | MUSC Foundation For Research Development (US) | 2011-11-09 | — | — | EP | disclosed |
| WO-2010078247-A1 | SPHINGO-GUANIDINES AND THEIR USE AS INHIBITORS OF SPHINGOSINE KINASE | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2010-07-08 | — | — | WO | disclosed |