SCHEMBL25786236

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25786217	0.90	MARK3 (0.41)	MARK3GSK3BCAMK2BMARK2MINK1
	SCHEMBL25786240	0.88	KDM4E (0.37)	MARK3GSK3BCAMK2BMARK2MINK1
	SCHEMBL25251553	0.85	TP53 (0.36)	KDM4EALDH1A1HPGDMAPK8
	SCHEMBL25786244	0.85	BAD (0.33)	MARK3GSK3BCAMK2BMARK2MINK1
	SCHEMBL25786243	0.85	MCL1 (0.36)	MARK3GSK3BCAMK2BMARK2MINK1
	SCHEMBL25786239	0.83	MAPK8 (0.35)	MARK3GSK3BCAMK2BMARK2MINK1
	SCHEMBL25793333	0.81	MARK3 (0.39)	MARK3GSK3BCAMK2BMARK2MINK1
	SCHEMBL25786229	0.78	BAD (0.42)	BADBCL2MCL1BCL2L1PMAIP1
	SCHEMBL25786224	0.77	BAD (0.43)	BADBCL2MCL1BCL2L1PMAIP1
	SCHEMBL25786617	0.77	BAD (0.45)	BADBCL2MCL1BCL2L1PMAIP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.