Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | SOS1 | Q07889 | 6/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KRAS | P01116 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20169405 | 0.84 | SLC6A2 (0.37) | CA1CA2ACHESOS1ALDH1A1 | |
| SCHEMBL10933460 | 0.79 | CA1 (0.53) | CA1CA2ACHEALDH1A1SMN1; SMN2 | |
| SCHEMBL26698513 | 0.78 | KDM4E (0.54) | ALDH1A1 | |
| SCHEMBL25786453 | 0.76 | ALDH1A1 (0.50) | CA1CA2ACHEALDH1A1SLC6A4 | |
| SCHEMBL12697206 | 0.73 | TDP1 (0.43) | ALDH1A1SMN1; SMN2ALOX12 | |
| SCHEMBL3054988 | 0.72 | CA1 (0.46) | CA1CA2ACHESOS1ALDH1A1 | |
| SCHEMBL15223665 | 0.70 | NPSR1 (0.41) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL2401390 | 0.69 | CYP2D6 (0.61) | CA1CA2ACHEALDH1A1SLC6A4 | |
| SCHEMBL19286309 | 0.69 | CA1 (0.58) | CA1CA2ACHEALDH1A1SLC6A4 | |
| SCHEMBL20376231 | 0.69 | CYP2D6 (0.61) | CA1CA2ACHEALDH1A1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |