Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24729872 | 0.84 | BRAF (0.52) | BRAFMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL20731984 | 0.83 | BRAF (0.51) | BRAFMEN1KMT2AALDH1A1RPS6KB1 | |
| SCHEMBL23938006 | 0.79 | FABP1 (0.55) | BRAFMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL2261348 | 0.77 | ALDH1A1 (0.57) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL30874824 | 0.76 | ALDH1A1 (0.56) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL32666863 | 0.75 | PTK2 (0.59) | KMT2ANPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL5555378 | 0.75 | PTK2 (0.59) | KMT2ANPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL25068994 | 0.74 | FFAR1 (0.55) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL27428918 | 0.73 | NPSR1 (0.52) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL2991022 | 0.72 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1RAB9ARPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |