Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 17/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 16/20 | 0.50 |
| ▸ | GSK3B | P49841 | 8/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25786520 | 0.86 | CCNE1 (0.39) | CDK2CCNE1GSK3BDGAT1 | |
| SCHEMBL25786522 | 0.84 | CDK2 (0.52) | CDK2CCNE1GSK3B | |
| SCHEMBL25781986 | 0.79 | CDK2 (0.61) | CDK2CCNE1GSK3B | |
| SCHEMBL25786613 | 0.78 | CDK2 (0.58) | CDK2CCNE1GSK3B | |
| SCHEMBL1371116 | 0.76 | JAK2 (0.50) | DGAT1 | |
| SCHEMBL25785761 | 0.73 | CDK2 (0.54) | CDK2CCNE1GSK3B | |
| SCHEMBL25786525 | 0.72 | CDK2 (0.75) | CDK2CCNE1GSK3B | |
| SCHEMBL25786517 | 0.71 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL30539218 | 0.70 | CDK2 (0.49) | CDK2CCNE1GSK3B | |
| SCHEMBL25785308 | 0.70 | CDK2 (0.49) | CDK2CCNE1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116884-A1 | CDK2 INHIBITORS AND USE THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2023-06-29 | — | — | WO | disclosed |