Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25787374 | 0.90 | MAPT (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL25787489 | 0.86 | HDAC6 (0.48) | HSD17B10NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8370275 | 0.81 | NPC1 (0.66) | HSD17B10NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL25788974 | 0.81 | NPC1 (0.58) | HSD17B10NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3950334 | 0.81 | NPC1 (0.54) | HSD17B10NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL18235580 | 0.74 | NPC1 (0.69) | NPC1RAB9ASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL1748262 | 0.73 | HDAC6 (0.51) | HSD17B10NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL33525260 | 0.73 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL25788987 | 0.73 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL8367944 | 0.70 | NPC1 (0.55) | HSD17B10NPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121022-A1 | NOVEL LEUKOTRIENE B4 RECEPTOR INHIBITORS AND USE THEREOF | 이화여자대학교 산학협력단 | 2023-06-29 | — | — | WO | disclosed |