Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.55 |
| ▸ | IL6 | P05231 | 1/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.48 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25788987 | 1.00 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2USP2MAPK10 | |
| SCHEMBL33525283 | 0.88 | IL6 (0.65) | NPC1RAB9ASMN1; SMN2IL6STAT3 | |
| SCHEMBL11814248 | 0.88 | IL6 (0.59) | NPC1RAB9ASMN1; SMN2IL6STAT3 | |
| SCHEMBL1748262 | 0.85 | HDAC6 (0.51) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL8370275 | 0.85 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL25788974 | 0.85 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2USP2MAPK10 | |
| SCHEMBL25248622 | 0.82 | IL6 (0.51) | NPC1RAB9ASMN1; SMN2IL6STAT3 | |
| SCHEMBL25787489 | 0.82 | HDAC6 (0.48) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL29972698 | 0.78 | NPC1 (0.75) | NPC1RAB9ASMN1; SMN2IL6STAT3 | |
| SCHEMBL1699100 | 0.78 | NPC1 (0.75) | NPC1RAB9ASMN1; SMN2IL6STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260092043-A1 | NOVEL BENZOXAZOLE DERIVATIVE COMPRISING 4-AMINO-BUTANAMIDE AND USE THEREOF | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION | 2026-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260092043-A1 | NOVEL BENZOXAZOLE DERIVATIVE COMPRISING 4-AMINO-BUTANAMIDE AND USE THEREOF | IL4I1, GABRB1, IL1B | NPC1 2359/4885RAB9A 1904/4885SMN1; SMN2 2841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.