Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.56 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | HTR6 | P50406 | 7/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | BAD | Q92934 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25790949 | 0.82 | HTR2C (0.47) | HTR2CHTR2AMCL1BADBCL2 | |
| SCHEMBL23927902 | 0.79 | HTR2C (0.64) | HTR2CHTR2AHTR6KDM4EHTR1D | |
| SCHEMBL30637141 | 0.78 | HTR2C (0.48) | HTR2C | |
| SCHEMBL31703512 | 0.78 | HTR2C (0.59) | HTR2CHTR2AHTR6MCL1CNR2 | |
| SCHEMBL25438171 | 0.78 | HTR2C (0.59) | HTR2CHTR2AHTR6MCL1CNR2 | |
| Fumaric Acid SCHEMBL23927840 | 0.77 | HTR2C (0.55) | HTR2CHTR2AHTR6MCL1KDM4E | |
| Fumaric Acid SCHEMBL29435352 | 0.77 | HTR2C (0.55) | HTR2CHTR2AHTR6MCL1KDM4E | |
| SCHEMBL24994243 | 0.75 | KDM4E (0.44) | HTR2CHTR2ACNR2KDM4EMEN1 | |
| SCHEMBL15999003 | 0.74 | HTR2C (0.65) | HTR2CHTR2AHTR6MCL1CNR2 | |
| SCHEMBL15999000 | 0.73 | HTR2C (0.60) | HTR2CHTR2AHTR6CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122320-A1 | POLYPODAL SEROTONERGIC COMPOUNDS AND PRODRUGS OF SEROTONIN RECEPTOR AGONISTS AND ANTAGONISTS | KULEON LLC (US) | 2023-06-29 | — | — | WO | disclosed |