Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | PPARA | Q07869 | 4/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.33 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.33 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.33 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.33 |
| ▸ | BAD | Q92934 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25790909 | 0.82 | HTR2C (0.56) | HTR2CHTR2AMCL1MEN1KMT2A | |
| SCHEMBL23927922 | 0.81 | HTR2C (0.70) | HTR2CHTR2APRMT5KDM4E | |
| SCHEMBL23927920 | 0.81 | HTR2C (0.70) | HTR2CHTR2APRMT5KDM4E | |
| SCHEMBL25790950 | 0.75 | HTR2C (0.47) | HTR2CHTR2APRMT5MCL1 | |
| SCHEMBL15323414 | 0.68 | BCHE (0.43) | — | |
| SCHEMBL23927925 | 0.67 | HTR2C (0.47) | HTR2CHTR2APRMT5MEN1KMT2A | |
| SCHEMBL23927923 | 0.67 | HTR2C (0.47) | HTR2CHTR2APRMT5MEN1KMT2A | |
| SCHEMBL23956112 | 0.67 | HTR2C (0.47) | HTR2CHTR2APRMT5KDM4E | |
| SCHEMBL25520783 | 0.66 | HTR2C (0.44) | HTR2CHTR2AKMT2A | |
| SCHEMBL23956087 | 0.66 | HTR2C (0.46) | HTR2CHTR2APRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122320-A1 | POLYPODAL SEROTONERGIC COMPOUNDS AND PRODRUGS OF SEROTONIN RECEPTOR AGONISTS AND ANTAGONISTS | KULEON LLC (US) | 2023-06-29 | — | — | WO | disclosed |