Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGAV | P06756 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29780341 | 0.81 | HTR2C (0.69) | HTR2CHTR2AMTNR1AMTNR1BHDAC8 | |
| SCHEMBL23956071 | 0.81 | HTR2C (0.69) | HTR2CHTR2AMTNR1AMTNR1BHDAC8 | |
| SCHEMBL23927896 | 0.81 | HTR2C (0.69) | HTR2CHTR2AMTNR1AMTNR1BHDAC8 | |
| SCHEMBL23927895 | 0.81 | HTR2C (0.69) | HTR2CHTR2AMTNR1AMTNR1BHDAC8 | |
| Fumaric Acid SCHEMBL25201003 | 0.79 | HTR2C (0.56) | HTR2CITGB3ITGAVHTR2AMTNR1A | |
| Fumaric Acid SCHEMBL30729586 | 0.79 | HTR2C (0.56) | HTR2CITGB3ITGAVHTR2AMTNR1A | |
| Fumaric Acid SCHEMBL27125871 | 0.79 | HTR2C (0.56) | HTR2CITGB3ITGAVHTR2AMTNR1A | |
| SCHEMBL25236285 | 0.77 | HTR2C (0.59) | HTR2CITGB3ITGAVHTR2AMTNR1A | |
| SCHEMBL23956079 | 0.76 | HTR2C (0.51) | HTR2CMAOAMAOBHTR2APRMT5 | |
| SCHEMBL23956076 | 0.76 | HTR2C (0.51) | HTR2CMAOAMAOBHTR2APRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122320-A1 | POLYPODAL SEROTONERGIC COMPOUNDS AND PRODRUGS OF SEROTONIN RECEPTOR AGONISTS AND ANTAGONISTS | KULEON LLC (US) | 2023-06-29 | — | — | WO | disclosed |