Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | LSS | P48449 | 3/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD5 | P21918 | 1/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159409 | 1.00 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KCNH2LSS | |
| SCHEMBL14320804 | 0.89 | SLC18A3 (0.46) | SLC6A2SLC6A4SLC6A3KCNH2LSS | |
| SCHEMBL23469162 | 0.84 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3KCNH2LSS | |
| SCHEMBL12950820 | 0.84 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3KCNH2LSS | |
| SCHEMBL12925934 | 0.83 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3KCNH2LSS | |
| SCHEMBL4893089 | 0.82 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3KCNH2LSS | |
| SCHEMBL24310166 | 0.82 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KCNH2LSS | |
| SCHEMBL24394469 | 0.82 | KCNH2 (0.54) | SLC6A2SLC6A4SLC6A3KCNH2LSS | |
| SCHEMBL2077734 | 0.82 | KCNH2 (0.54) | SLC6A2SLC6A4SLC6A3KCNH2LSS | |
| SCHEMBL24394470 | 0.82 | KCNH2 (0.54) | SLC6A2SLC6A4SLC6A3KCNH2LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3668857-B1 | PROCESSES FOR THE PREPARATION OF NIRAPARIB AND INTERMEDIATES THEREOF | TEVA PHARMACEUTICALS INT GMBH (CH) | 2023-07-05 | — | — | EP | disclosed |