Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25792829 | 0.78 | CA2 (0.32) | CA2 | |
| SCHEMBL11459973 | 0.76 | CYP1A2 (0.38) | CYP1A2HSD17B10KDM4EALDH1A1 | |
| SCHEMBL24812432 | 0.76 | CA12 (0.40) | KDM4ECA2 | |
| SCHEMBL15241254 | 0.75 | — | — | |
| SCHEMBL1792611 | 0.73 | — | — | |
| SCHEMBL10835191 | 0.72 | CA2 (0.44) | KDM4ECA2 | |
| SCHEMBL16546847 | 0.72 | CA2 (0.44) | KDM4ECA2 | |
| SCHEMBL299301 | 0.72 | CA2 (0.44) | KDM4ECA2 | |
| SCHEMBL125676 | 0.72 | CA2 (0.44) | KDM4ECA2 | |
| SCHEMBL5668460 | 0.72 | CA2 (0.44) | KDM4ECA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |