Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 9/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18053621 | 0.84 | USP2 (0.59) | USP2SMN1; SMN2MGLLTSHRRECQL | |
| SCHEMBL1855329 | 0.80 | SMN1; SMN2 (0.46) | USP2SMN1; SMN2NAMPTTSHRRECQL | |
| SCHEMBL14802585 | 0.79 | SMN1; SMN2 (0.66) | USP2SMN1; SMN2TSHRRECQL | |
| SCHEMBL4278413 | 0.77 | USP2 (0.54) | USP2SMN1; SMN2MGLLTSHRRECQL | |
| SCHEMBL30267043 | 0.77 | USP2 (0.41) | USP2SMN1; SMN2NAMPTTSHRGPR119 | |
| SCHEMBL1848025 | 0.77 | HPGD (0.47) | USP2SMN1; SMN2TSHRKMT2A | |
| SCHEMBL15166534 | 0.76 | KMT2A (0.39) | USP2SMN1; SMN2NAMPTGPR119KMT2A | |
| SCHEMBL879545 | 0.75 | HPGD (0.50) | USP2SMN1; SMN2KMT2A | |
| SCHEMBL2960741 | 0.75 | USP2 (0.51) | USP2SMN1; SMN2MGLLNAMPTRECQL | |
| SCHEMBL15160794 | 0.74 | HTR1A (0.43) | USP2SMN1; SMN2MGLLTSHRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130054-A2 | HETEROARYL COMPOUNDS AS INHIBITORS OF IRAK4, COMPOSITIONS AND APPLICATIONS THEREOF | ACCRO BIOSCIENCE (HK) LIMITED (CN) | 2023-07-06 | — | — | WO | disclosed |