SCHEMBL25794080

SCHEMBL25794080

CCC(=O)NCCS(=O)(=O)C(C)C

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
ALDH1A1 P00352 1/20 0.35
RECQL P46063 1/20 0.34
PSMB5 P28074 1/20 0.34
GRIA1 P42261 3/20 0.33
CYP2C9 P11712 1/20 0.32
MTNR1A P48039 1/20 0.32
MTNR1B P49286 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23228566 0.79 HPGD (0.36) ALDH1A1
SCHEMBL15932499 0.79 KDM4E (0.44) ALDH1A1GRIA1MTNR1AMTNR1B
SCHEMBL20232720 0.78 KMT2A (0.40) MEN1KMT2AALDH1A1RECQLCYP2C9
SCHEMBL18362143 0.77 MEN1 (0.56) MEN1KMT2ARECQLMTNR1AMTNR1B
SCHEMBL6889241 0.77 MEN1 (0.62) MEN1KMT2AALDH1A1RECQL
SCHEMBL22917237 0.76 GRIA1 (0.52) MEN1KMT2AALDH1A1RECQLPSMB5
SCHEMBL20942602 0.75 MEN1 (0.54) MEN1KMT2AALDH1A1RECQL
SCHEMBL24811358 0.74 MEN1 (0.44) MEN1KMT2AALDH1A1RECQLPSMB5
SCHEMBL18857429 0.74 ALDH1A1 (0.36) ALDH1A1
SCHEMBL24334705 0.73 MEN1 (0.52) MEN1KMT2ARECQLMTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023122298-A1 PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS Stablix, Inc. (US) 2023-06-29 WO disclosed