Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGK1 | O00141 | 4/20 | 0.33 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2117332 | 0.79 | KCNJ1 (0.44) | KCNJ1PIK3CDPIK3CBMTORPIK3CG | |
| SCHEMBL3467686 | 0.71 | KDM4E (0.38) | ALDH1A1MAPT | |
| SCHEMBL2117741 | 0.68 | SLC22A12 (0.49) | SGK1 | |
| SCHEMBL2119426 | 0.68 | SGK1 (0.45) | SGK1MTORALDH1A1TP53 | |
| SCHEMBL2120149 | 0.68 | TRIM24 (0.48) | MTORALDH1A1TP53MAPT | |
| SCHEMBL2121436 | 0.67 | POLB (0.51) | PIK3CDPIK3CBMTORPIK3CGALDH1A1 | |
| SCHEMBL2118346 | 0.67 | MAPT (0.40) | TP53MAPT | |
| SCHEMBL2117129 | 0.63 | LMNA (0.47) | KCNJ1PIK3CDPIK3CBMTORPIK3CG | |
| SCHEMBL2119625 | 0.63 | SGK1 (0.41) | SGK1ALDH1A1TP53 | |
| SCHEMBL2120158 | 0.62 | TP53 (0.40) | SGK1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382190-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE AS-INHIBITORS | European Molecular Biology Laboratory (EMBL) (DE) | 2011-11-02 | — | — | EP | disclosed |