SCHEMBL2579647

SCHEMBL2579647

C=CCC(CCCCB1OC(C)(C)C(C)(C)O1)(NC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AAK1 Q2M2I8 2/20 0.34
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL895703 1.00 AAK1 (0.34) AAK1MAPT
SCHEMBL894967 0.90 AAK1 (0.34) AAK1MAPT
SCHEMBL894969 0.90 AAK1 (0.34) AAK1MAPT
SCHEMBL20677462 0.90 AAK1 (0.34) AAK1
SCHEMBL2567542 0.90 AAK1 (0.35) AAK1
SCHEMBL895228 0.88 THRB (0.33) AAK1MAPT
SCHEMBL21064760 0.85 AAK1 (0.36) AAK1
SCHEMBL20243183 0.85
SCHEMBL10207132 0.85
SCHEMBL895372 0.84 AAK1 (0.34) AAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2560978-A1 INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS Mars, Incorporated (US) 2013-02-27 EP disclosed
WO-2011133653-A1 INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS MARS, INCORPORATED (US) 2011-10-27 WO disclosed