Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25812710 | 1.00 | ATF4 (0.53) | ATF4 | |
| SCHEMBL25781052 | 0.93 | ATF4 (0.49) | ATF4 | |
| SCHEMBL25796804 | 0.90 | ATF4 (0.53) | ATF4 | |
| SCHEMBL25804693 | 0.88 | ATF4 (0.50) | ATF4 | |
| SCHEMBL20992251 | 0.86 | ATF4 (0.49) | ATF4 | |
| SCHEMBL20992524 | 0.86 | ATF4 (0.51) | ATF4 | |
| SCHEMBL20992410 | 0.85 | ATF4 (0.50) | ATF4 | |
| SCHEMBL20992455 | 0.85 | ATF4 (0.50) | ATF4 | |
| SCHEMBL19568607 | 0.85 | ATF4 (0.50) | ATF4 | |
| SCHEMBL25812815 | 0.85 | ATF4 (0.51) | ATF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452456-B1 | BICYCLIC MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2023-07-05 | — | — | EP | disclosed |