Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 5/20 | 0.46 |
| ▸ | METAP2 | P50579 | 2/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1273919 | 0.94 | CHEK1 (0.73) | CHEK1MAPTKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL15640013 | 0.92 | CHEK1 (0.70) | CHEK1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL29769140 | 0.85 | CHEK1 (0.58) | CHEK1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8404434 | 0.85 | CHEK1 (0.58) | CHEK1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL29589219 | 0.83 | CHEK1 (1.00) | CHEK1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL2268059 | 0.83 | CHEK1 (1.00) | CHEK1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL28294330 | 0.81 | CHEK1 (0.95) | CHEK1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL722064 | 0.80 | AXL (0.56) | CHEK1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL14389670 | 0.80 | CHEK1 (0.70) | CHEK1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL1744194 | 0.79 | CHEK1 (0.45) | CHEK1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021070416-A1 | THERMOSETTING RESIN COMPOSITION, CURED PRODUCT THEREOF, AND STRUCTURAL BODY INCLUDING SAID CURED PRODUCT | 昭和電工株式会社 | 2021-04-15 | — | — | WO | claimed |
| EP-0904769-B1 | Keratin fibre dye compositions containing Indazole amine derivatives and dyeing method | OREAL (FR) | 2002-09-25 | — | — | EP | claimed |
| US-20240174647-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. | 2024-05-30 | — | — | US | disclosed |
| WO-2024073073-A2 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. (US) | 2024-04-04 | — | — | WO | disclosed |
| WO-2021070416-A1 | THERMOSETTING RESIN COMPOSITION, CURED PRODUCT THEREOF, AND STRUCTURAL BODY INCLUDING SAID CURED PRODUCT | 昭和電工株式会社 | 2021-04-15 | — | — | WO | disclosed |
| US-8598078-B2 | Condensed anthran I lami de derivatives as insecticides | SYNGENTA CROP PROTECTION, LLC (US) | 2013-12-03 | — | — | US | disclosed |
| US-8435990-B2 | Dihydropyrimidone amides as P2X7 modulators | ROCHE PALO ALTO LLC (US) | 2013-05-07 | — | — | US | disclosed |
| US-8377983-B2 | Benzazole derivatives, compositions, and methods of use as aurora kinase inhibitors | TRANSTECH PHARMA, INC. (US) | 2013-02-19 | — | — | US | disclosed |
| CN-102633783-A | Benzazole derivatives, compositions, and methods of use as aurora kinase inhibitors | TRANSTECH PHARMA INC | 2012-08-15 | — | — | CN | disclosed |
| CN-101379060-B | Benzoxazole-based derivatives as Aurora kinase inhibitors, compositions, and methods of use | TRANSTECH PHARMA INC | 2012-05-23 | — | — | CN | disclosed |
| EP-2178859-B1 | CONDENSED ANTHRANILAMIDE DERIVATIVES AS INSECTISIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-21 | — | — | EP | disclosed |
| CN-101379060-A | Benzoxazole-based derivatives as Aurora kinase inhibitors, compositions, and methods of use | TRANSTECH PHARMA INC (US) | 2009-03-04 | — | — | CN | disclosed |
| WO-2009024341-A2 | CONDENSED ANTHRAN I LAMI DE DERIVATIVES AS INSECTISIDES | SYNGENTA PARTICIPATIONS AG, (CH) | 2009-02-26 | — | — | WO | disclosed |
| EP-1987028-A2 | BENZAZOLE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE AS AURORA KINASE INHIBITORS | Transtech Pharma, Inc. (US) | 2008-11-05 | — | — | EP | disclosed |
| US-7273863-B1 | Benzophenones as inhibitors of reverse transcriptase | SMITHKLINE BEECHAM CORPORATION (US) | 2007-09-25 | — | — | US | disclosed |
| US-20070219235-A1 | Benzazole derivatives, compositions, and methods of use as aurora kinase inhibitors | VTVX HOLDINGS I LLC | 2007-09-20 | — | — | US | disclosed |
| WO-2007095124-A2 | BENZAZOLE DERIVATIVES, COMPOSITIONS, AND METHODS OF USE AS AURORA KINASE INHIBITORS | TRANSTECH PHARMA, INC. (US) | 2007-08-23 | — | — | WO | disclosed |
| US-6027538-A | OXIDATION DYEING OF KERATINOUS FIBERS CONTAINING AT LEAST ONE COUPLER SELECTED FROM INDAZOLEAMINE DERIVATIVES AND AT LEAST ONE OXIDATION BASE; POWERFUL, NOT VERY SELECTIVE HAIR DYES WHICH ARE CAPABLE OF GENERATING INTENSE COLOR | L'OREAL S.A. (FR) | 2000-02-22 | — | — | US | disclosed |
| US-4352931-A | Lin-benzoaminopurinols | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1982-10-05 | — | — | US | disclosed |
| EP-0040872-A1 | Pyrazolo-quinazoline derivatives and methods of producing such derivatives | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1981-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240174647-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | LRRK2, MAP3K20, MAP3K5 | CHEK1 175/4885MAPT 623/4885KDM4E 1085/4885 |
| US-20070219235-A1 | Benzazole derivatives, compositions, and methods of use as aurora kinase inhibitors | AURKC, AURKA, AURKB | CHEK1 11/4885MAPT 1464/4885KDM4E 769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.