Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL997537 | 0.95 | TDP1 (0.38) | TDP1TSHRTGFBR1ALDH1A1FFAR3 | |
| Methacrylic Acid SCHEMBL890470 | 0.95 | TDP1 (0.38) | TDP1TSHRTGFBR1ALDH1A1FFAR3 | |
| Methacrylic Acid SCHEMBL1054360 | 0.95 | TDP1 (0.38) | TDP1TSHRTGFBR1ALDH1A1FFAR3 | |
| Methacrylic Acid SCHEMBL17685022 | 0.95 | TDP1 (0.38) | TDP1TSHRTGFBR1ALDH1A1FFAR3 | |
| Methacrylic Acid SCHEMBL28072771 | 0.92 | TDP1 (0.36) | TDP1TSHRTGFBR1ALDH1A1FFAR3 | |
| Methacrylic Acid SCHEMBL7648519 | 0.89 | TDP1 (0.38) | TDP1TSHRTGFBR1ALDH1A1FFAR3 | |
| Methacrylic Acid SCHEMBL28145674 | 0.89 | TDP1 (0.38) | TDP1TSHRTGFBR1ALDH1A1FFAR3 | |
| Methacrylic Acid SCHEMBL27304642 | 0.87 | TSHR (0.33) | TDP1TSHRTGFBR1ALDH1A1FFAR3 | |
| Methacrylic Acid SCHEMBL27304641 | 0.87 | TSHR (0.33) | TDP1TSHRTGFBR1ALDH1A1FFAR3 | |
| Methacrylic Acid SCHEMBL28463453 | 0.86 | TDP1 (0.36) | TDP1TSHRTGFBR1ALDH1A1FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1566161-B1 | Flowable liner material | HERAEUS KULZER GMBH (DE) | 2011-11-09 | — | — | EP | disclosed |
| US-7425587-B2 | Flowable underfilling material | HERAECUS KULZER GMBH (DE) | 2008-09-16 | — | — | US | disclosed |
| US-20050192375-A1 | Easily visible and distinguishable from tooth substance; free radical polymerizable monomers, photoinitiator and white pigment; cavity restoration | HERAEUS KULZER GMBH (DE) | 2005-09-01 | — | — | US | disclosed |
| EP-1566161-A1 | Flowable liner material | Heraeus Kulzer GmbH (DE) | 2005-08-24 | — | — | EP | disclosed |