Methacrylic Acid

Methacrylic Acid

SCHEMBL890470

C=C(C)C(=O)O.C=C(C)C(=O)O.CCCO

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.38
TSHR P16473 2/20 0.37
TGFBR1 P36897 1/20 0.37
FFAR3 O14843 3/20 0.36
HDAC1 Q13547 2/20 0.36
HDAC2 Q92769 2/20 0.36
HDAC3 O15379 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
ALDH1A1 P00352 3/20 0.35
THRB P10828 2/20 0.33
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
PGGT1B P53609 1/20 0.33
LCK P06239 1/20 0.33
FYN P06241 1/20 0.33
ALOX15 P16050 1/20 0.32
CHRM1 P11229 1/20 0.32
AKR1A1 P14550 1/20 0.32
CHRM3 P20309 1/20 0.32
HTR2A P28223 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL17685022 1.00 TDP1 (0.38) TDP1TSHRTGFBR1FFAR3HDAC1
Methacrylic Acid SCHEMBL997537 1.00 TDP1 (0.38) TDP1TSHRTGFBR1FFAR3HDAC1
Methacrylic Acid SCHEMBL1054360 1.00 TDP1 (0.38) TDP1TSHRTGFBR1FFAR3HDAC1
Methacrylic Acid SCHEMBL28072771 0.97 TDP1 (0.36) TDP1TSHRTGFBR1FFAR3HDAC1
Methacrylic Acid SCHEMBL2579771 0.95 TDP1 (0.35) TDP1TSHRTGFBR1FFAR3HDAC1
Methacrylic Acid SCHEMBL27304641 0.92 TSHR (0.33) TDP1TSHRTGFBR1FFAR3HDAC1
Methacrylic Acid SCHEMBL27304642 0.92 TSHR (0.33) TDP1TSHRTGFBR1FFAR3HDAC1
Methacrylic Acid SCHEMBL28463453 0.92 TDP1 (0.36) TDP1TSHRTGFBR1FFAR3HDAC1
Methacrylic Acid SCHEMBL22325631 0.90 TGFBR1 (0.36) TDP1TSHRTGFBR1FFAR3HDAC1
Methacrylic Acid SCHEMBL11405100 0.88 TDP1 (0.38) TDP1TSHRTGFBR1FFAR3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3338756-B1 STORAGE-STABLE RESIN-MODIFIED GLASS IONOMER CEMENT VOCO GMBH (DE) 2020-02-26 EP claimed
EP-2716276-B1 Kit and method for indirect chair-side production of composite inlays VOCO GMBH (DE) 2019-04-24 EP claimed
EP-3338756-A1 STORAGE-STABLE RESIN-MODIFIED GLASS IONOMER CEMENT VOCO GmbH (DE) 2018-06-27 EP claimed
EP-2374444-B1 Dental covering material VOCO GMBH (DE) 2017-03-01 EP claimed
EP-2698142-B1 Dental filling materials and dental varnish for the inhibition of biofilm formation of streptococcus mutans, and their preparation VOCO GMBH (DE) 2017-02-01 EP claimed
US-9326917-B2 Dental masking compound VOCO GMBH (DE) 2016-05-03 US claimed
US-9320682-B2 Tooth filling materials and dental varnish for inhibiting the formation of a biofilm of Streptococcus mutans and the production thereof VOCO GMBH (DE) 2016-04-26 US claimed
EP-2374445-B1 Dual hardening multi-component dental composition VOCO GMBH (DE) 2015-07-29 EP claimed
US-20140051036-A1 TOOTH FILLING MATERIALS AND DENTAL VARNISH FOR INHIBITING THE FORMATION OF A BIOFILM OF STREPTOCOCCUS MUTANS AND THE PRODUCTION THEREOF HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH (DE) 2014-02-20 US claimed
EP-2698142-A2 Dental filling materials and dental varnish for the inhibition of biofilm formation of streptococcus mutans, and their preparation VOCO GmbH (DE) 2014-02-19 EP claimed
US-8501834-B2 Dual-curing, multi-component dental composition VOCO GMBH (DE) 2013-08-06 US claimed
US-20120093741-A1 DENTAL MASKING COMPOUND VOCO GMBH (DE) 2012-04-19 US claimed
US-20110250558-A1 DUAL-CURING, MULTI-COMPONENT DENTAL COMPOSITION VOCO GMBH (DE) 2011-10-13 US claimed
EP-2374444-A2 Dental covering material VOCO GmbH (DE) 2011-10-12 EP claimed
EP-2374445-A2 Dual hardening multi-component dental composition VOCO GmbH (DE) 2011-10-12 EP claimed
EP-3011949-B1 CURABLE DENTAL MATERIAL VOCO GMBH (DE) 2021-05-05 EP disclosed
EP-3338756-B1 STORAGE-STABLE RESIN-MODIFIED GLASS IONOMER CEMENT VOCO GMBH (DE) 2020-02-26 EP disclosed
US-5374682-A Hard, acid resistant automobile topcoatings NIPPON PAINT CO., LTD. (JP) 1994-12-20 US disclosed
EP-0250183-B1 COATING POWDER Nippon Paint Co., Ltd. (JP) 1993-09-22 EP disclosed
EP-0250183-A2 Coating powder Nippon Paint Co., Ltd. (JP) 1987-12-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140051036-A1 TOOTH FILLING MATERIALS AND DENTAL VARNISH FOR INHIBITING THE FORMATION OF A BIOFILM OF STREPTOCOCCUS MUTANS AND THE PRODUCTION THEREOF SRM, SMS, GMPS TDP1 2443/4885TSHR 3521/4885TGFBR1 2455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.