SCHEMBL2579838

SCHEMBL2579838

C=CC(=O)O[Si](OC(C)C)(OC(C)C)OC(C)C

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.42
HPGD P15428 1/20 0.32
ALDH1A1 P00352 4/20 0.31
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
CYP3A4 P08684 1/20 0.31
HSD17B10 Q99714 1/20 0.31
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8605586 0.80 TSHR (0.46) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9082756 0.78 TSHR (0.40) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL587049 0.75 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL31252378 0.75 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL475926 0.73 TSHR (0.45) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27511672 0.72 TSHR (0.38) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27743559 0.72 TSHR (0.34) TSHR
SCHEMBL2313926 0.72 TSHR (0.43) TSHRALDH1A1
SCHEMBL7036189 0.71 TSHR (0.43) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2744364 0.71 TSHR (0.38) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112266708-A Developable anti-sand-blasting multifunctional protective material and preparation method and application thereof 中科院广州化学有限公司 2021-01-26 CN claimed
CN-110461894-B Curable composition, method for producing same, and article using same 大金工业株式会社 2022-09-02 CN disclosed
CN-109476795-B Curable composition, method for producing same, and article using same 大金工业株式会社 2022-05-06 CN disclosed
CN-113956464-A Compound having isocyanuric skeleton and composition comprising same 大金工业株式会社 2022-01-21 CN disclosed
CN-109715702-B Novel compound having isocyanuric skeleton and composition comprising same 大金工业株式会社 2021-11-23 CN disclosed
CN-112266708-A Developable anti-sand-blasting multifunctional protective material and preparation method and application thereof 中科院广州化学有限公司 2021-01-26 CN disclosed
US-9946158-B2 Composition for forming resist underlayer film for nanoimprint NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-04-17 US disclosed
EP-2461350-B1 USE OF A COMPOSITION FOR FORMING RESIST UNDERLAYER FILM FOR NANOIMPRINT LITHOGRAPHY NISSAN CHEMICAL IND LTD (JP) 2018-02-28 EP disclosed
US-20150099070-A1 COMPOSITION FOR FORMING RESIST UNDERLAYER FILM FOR NANOIMPRINT NISSAN CHEMICAL IND LTD (JP) 2015-04-09 US disclosed
EP-2461350-A1 COMPOSITION FOR FORMING RESIST UNDERLAYER FILM FOR NANOIMPRINT LITHOGRAPHY Nissan Chemical Industries, Ltd. (JP) 2012-06-06 EP disclosed
US-20120128891-A1 COMPOSITION FOR FORMING RESIST UNDERLAYER FILM FOR NANOIMPRINT NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-05-24 US disclosed
US-8048615-B2 Silicon-containing resist underlayer coating forming composition for forming photo-crosslinking cured resist underlayer coating NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2011-11-01 US disclosed
US-20090162782-A1 Silicon-Containing Resist Underlayer Coating Forming Composition for Forming Photo-Crosslinking Cured Resist Underlayer Coating NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-06-25 US disclosed
EP-1972998-A1 SILICON-CONTAINING RESIST UNDERLYING LAYER FILM FORMING COMPOSITION FOR FORMATION OF PHOTOCROSSLINKING CURED RESIST UNDERLYING LAYER FILM Nissan Chemical Industries, Ltd. (JP) 2008-09-24 EP disclosed