SCHEMBL587049

SCHEMBL587049

C=CC(=O)O[Si](OC)(OC)OC

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.37
HPGD P15428 1/20 0.35
ALDH1A1 P00352 5/20 0.35
TP53 P04637 3/20 0.34
HIF1A Q16665 3/20 0.34
CYP3A4 P08684 2/20 0.34
HSD17B10 Q99714 1/20 0.34
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31252378 1.00 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A
Cyclopropane SCHEMBL9551499 0.93 TSHR (0.33) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL9082756 0.84 TSHR (0.40) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27500757 0.83 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28284442 0.82 TSHR (0.36) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2584602 0.78 TSHR (0.35) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28759990 0.78 TSHR (0.35) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28014604 0.78 TSHR (0.35) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2744364 0.76 TSHR (0.38) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2579838 0.75 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119081702-B Low-surface tension silicon dioxide etching solution and preparation method and application thereof 浙江尚能实业股份有限公司 2025-04-15 CN claimed
CN-119751800-A Organosilicon hybrid prepolymer, preparation method thereof and high-wear-resistance organosilicon leather containing same 山东德海友利新能源股份有限公司 2025-04-04 CN claimed
CN-119081702-A Low-surface tension silicon dioxide etching solution and preparation method and application thereof 浙江尚能实业股份有限公司 2024-12-06 CN claimed
CN-113817138-B UV-cured high-fluorine-content anti-fingerprint resin and preparation method and application thereof 长沙松润新材料有限公司 2024-10-01 CN claimed
CN-115181272-B Preparation method of modified MQ resin and acrylate adhesive prepared by using preparation method 黑龙江省科学院石油化学研究院 2023-08-18 CN claimed
CN-113913017-B Rubber composition, single-component dealcoholized silicone rubber and preparation method thereof 北京天山新材料技术有限公司 2023-04-28 CN claimed
CN-111533864-B Block copolymer and preparation method thereof, and all-solid-state copolymer electrolyte membrane and preparation method thereof 闽南师范大学 2022-12-23 CN claimed
CN-115181272-A Preparation method of modified MQ resin and acrylate adhesive prepared by using same 黑龙江省科学院石油化学研究院 2022-10-14 CN claimed
CN-114292554-B Modified nano-silica reinforced aqueous PVDF coating and preparation method thereof 上海水立方新材料有限公司 2022-07-26 CN claimed
CN-114292554-A Modified nano-silica reinforced aqueous PVDF coating and preparation method thereof 上海水立方新材料有限公司 2022-04-08 CN claimed
CN-102199875-A Treatment process for environment depollution textiles HENGYUANXIANG GROUP CO LTD 2011-09-28 CN claimed
CN-100503757-C Ultraviolet light solidifying paint containing POSS and its preparation method UNIV TONGJI (CN) 2009-06-24 CN claimed
US-20080182135-A1 MAGNETIC RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2008-07-31 US claimed
CN-100372897-C Nano-printing ink for digital code spray printing and its preparation method UNIV TONGJI (CN) 2008-03-05 CN claimed
US-20070275193-A1 Functional Materials and Novel Methods for the Fabrication of Microfluidic Devices NATIONAL SCIENCE FOUNDATION 2007-11-29 US claimed
JP-2007527784-A 2007-10-04 JP claimed
EP-1737574-A2 FUNCTIONAL MATERIALS AND NOVEL METHODS FOR THE FABRICATION OF MICROFLUIDIC DEVICES The University of North Carolina at Chapel Hill (US) 2007-01-03 EP claimed
CN-1718645-A A kind of nano-printing ink for digital code spray printing and preparation method thereof UNIV TONGJI (CN) 2006-01-11 CN claimed
CN-1718656-A A kind of ultraviolet-curing paint that contains POSS and preparation method thereof UNIV TONGJI (CN) 2006-01-11 CN claimed
WO-2005084191-A2 FUNCTIONAL MATERIALS AND NOVEL METHODS FOR THE FABRICATION OF MICROFLUIDIC DEVICES THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2005-09-15 WO claimed