Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.38 |
| ▸ | RORC | P51449 | 3/20 | 0.37 |
| ▸ | USP1 | O94782 | 1/20 | 0.36 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CCNK | O75909 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2574236 | 0.89 | PTGDR2 (0.46) | PTGDR2CHRM1RORCUSP1WDR48 | |
| SCHEMBL2574678 | 0.84 | PTGDR2 (0.64) | PTGDR2CHRM1RORCUSP1WDR48 | |
| SCHEMBL2585815 | 0.84 | PTGDR2 (0.46) | PTGDR2RORC | |
| SCHEMBL2570354 | 0.84 | PTGDR2 (0.53) | PTGDR2CHRM1RORCUSP1WDR48 | |
| SCHEMBL2570357 | 0.84 | PTGDR2 (0.53) | PTGDR2CHRM1RORCUSP1WDR48 | |
| SCHEMBL2570380 | 0.82 | PTGDR2 (0.55) | PTGDR2CHRM1RORCUSP1WDR48 | |
| SCHEMBL2572421 | 0.82 | PTGDR2 (0.51) | PTGDR2CHRM1RORCUSP1WDR48 | |
| SCHEMBL2572423 | 0.82 | PTGDR2 (0.51) | PTGDR2CHRM1RORCUSP1WDR48 | |
| SCHEMBL2577124 | 0.81 | PTGDR2 (0.54) | PTGDR2CHRM1RORCMPOKDM4E | |
| SCHEMBL2570703 | 0.74 | PTGDR2 (0.46) | PTGDR2RORCMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139881-B1 | QUINOLINES AND THEIR THERAPEUTIC USE | PULMAGEN THERAPEUTICS ASTHMA LTD (GB) | 2011-11-09 | — | — | EP | claimed |