Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.33 |
| ▸ | HTR3B | O95264 | 4/20 | 0.33 |
| ▸ | HTR3A | P46098 | 4/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.33 |
| ▸ | HTR1A | P08908 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18053587 | 1.00 | POLB (0.37) | POLBALDH1A1NPSR1HTR3EHTR3B | |
| SCHEMBL21133587 | 1.00 | POLB (0.37) | POLBALDH1A1NPSR1HTR3EHTR3B | |
| SCHEMBL17274205 | 1.00 | POLB (0.37) | POLBALDH1A1NPSR1HTR3EHTR3B | |
| SCHEMBL18053590 | 0.91 | POLB (0.34) | POLBALDH1A1NPSR1HTR3EHTR3B | |
| SCHEMBL18053581 | 0.91 | POLB (0.34) | POLBALDH1A1NPSR1HTR3EHTR3B | |
| SCHEMBL25801004 | 0.89 | POLB (0.36) | POLBALDH1A1NPSR1HTR3EHTR3B | |
| SCHEMBL17274206 | 0.89 | POLB (0.36) | POLBALDH1A1NPSR1HTR3EHTR3B | |
| SCHEMBL25800950 | 0.89 | POLB (0.32) | POLBHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL17274204 | 0.88 | HTR3E (0.36) | POLBALDH1A1NPSR1HTR3EHTR3B | |
| SCHEMBL25801001 | 0.88 | HTR3E (0.36) | POLBALDH1A1NPSR1HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218782-A1 | IMAGING METHODS USING DEUTERATED COMPOUNDS | GENENTECH, INC. (US) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218782-A1 | IMAGING METHODS USING DEUTERATED COMPOUNDS | SLC10A1, SLC9B2, RXFP1 | POLB 3748/4885ALDH1A1 1909/4885NPSR1 218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.