SCHEMBL25801112

SCHEMBL25801112

CCCCCCCCN(CCC(=O)OCCc1ccccc1)CCC(=O)OCCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.54
ICMT O60725 2/20 0.53
ALB P02768 2/20 0.53
TDP1 Q9NUW8 1/20 0.53
DRD2 P14416 2/20 0.52
OPRM1 P35372 2/20 0.52
DRD3 P35462 2/20 0.52
OPRD1 P41143 2/20 0.52
OPRK1 P41145 2/20 0.52
CA12 O43570 4/20 0.51
CA1 P00915 4/20 0.51
CA2 P00918 4/20 0.51
CA4 P22748 3/20 0.51
THRA P10827 3/20 0.50
THRB P10828 3/20 0.50
LTA4H P09960 1/20 0.48
DGKA P23743 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25801119 1.00 KCNH2 (0.54) KCNH2ICMTALBTDP1DRD2
SCHEMBL25801111 0.95 TDP1 (0.55) KCNH2ICMTALBTDP1DRD2
SCHEMBL25801116 0.93 TDP1 (0.54) ICMTALBTDP1DRD2OPRM1
SCHEMBL25801125 0.91 SCN1A (0.54) KCNH2TDP1OPRM1DRD3LTA4H
SCHEMBL25801123 0.88 SCN1A (0.54) KCNH2TDP1OPRM1DRD3LTA4H
SCHEMBL25801192 0.86 KCNH2 (0.55) KCNH2TDP1OPRM1DRD3LTA4H
SCHEMBL873318 0.86 DGKA (0.66) TDP1DGKA
SCHEMBL873938 0.86 DGKA (0.66) TDP1DGKA
SCHEMBL28381584 0.86 DGKA (0.66) TDP1DGKA
SCHEMBL8663024 0.86 DGKA (0.66) TDP1DGKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023125184-A1 TERTIARY AMINE LIPID COMPOUND AND USE THEREOF 华南理工大学 2023-07-06 WO disclosed