Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23694602 | 0.92 | TDP1 (0.62) | TDP1APPALOX5ALDH1A1NPC1 | |
| SCHEMBL23694599 | 0.88 | TDP1 (0.57) | TDP1APPALOX5ALDH1A1L3MBTL1 | |
| SCHEMBL23694596 | 0.84 | TDP1 (0.53) | TDP1APPALDH1A1NPC1RAB9A | |
| SCHEMBL16314358 | 0.84 | LTA4H (0.52) | TDP1ALDH1A1NPC1L3MBTL1CYP3A4 | |
| SCHEMBL25801122 | 0.84 | TDP1 (0.57) | TDP1APPALOX5ALDH1A1OPRM1 | |
| SCHEMBL22832718 | 0.83 | TDP1 (0.81) | TDP1APPALOX5HCAR2ALDH1A1 | |
| SCHEMBL9324850 | 0.83 | SMN1; SMN2 (0.55) | TDP1ALOX5ALDH1A1NPC1RAB9A | |
| SCHEMBL25801132 | 0.83 | TDP1 (0.64) | TDP1APPALOX5HCAR2ALDH1A1 | |
| SCHEMBL25801124 | 0.82 | TDP1 (0.55) | TDP1APPALOX5HCAR2ALDH1A1 | |
| SCHEMBL25801111 | 0.82 | TDP1 (0.55) | TDP1APPALOX5OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125184-A1 | TERTIARY AMINE LIPID COMPOUND AND USE THEREOF | 华南理工大学 | 2023-07-06 | — | — | WO | disclosed |