SCHEMBL25801506

SCHEMBL25801506

CCc1ccc2oc(CC#N)nc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.52
MAPT P10636 7/20 0.49
RAB9A P51151 6/20 0.49
MEN1 O00255 6/20 0.49
KMT2A Q03164 6/20 0.49
SMN1; SMN2 Q16637 6/20 0.49
ALDH1A1 P00352 5/20 0.49
NPC1 O15118 5/20 0.49
TP53 P04637 5/20 0.49
KDM4E B2RXH2 4/20 0.49
HPGD P15428 3/20 0.49
HSD17B10 Q99714 3/20 0.49
NFKB1 P19838 1/20 0.49
NFKB2 Q00653 1/20 0.49
RELA Q04206 1/20 0.49
TDP1 Q9NUW8 2/20 0.45
TSHR P16473 1/20 0.45
ALOX15 P16050 2/20 0.44
HTT P42858 1/20 0.44
POLB P06746 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10224642 0.84 GAA (0.69) GAAMAPTRAB9AMEN1KMT2A
SCHEMBL11331561 0.83 KDM4E (0.51) MAPTRAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL11324885 0.82 GAA (0.59) GAAMAPTRAB9AMEN1KMT2A
SCHEMBL30010034 0.78 MAPT (0.43) GAAMAPTRAB9AMEN1KMT2A
SCHEMBL16515861 0.78 CETP (0.42) MEN1KMT2AGRK6
SCHEMBL7114426 0.78 GRK6 (0.59) GAAMAPTRAB9AMEN1KMT2A
SCHEMBL8626880 0.78 PSMB8 (0.59) MAPTRAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL3087532 0.78 GAA (0.52) GAAMAPTRAB9ASMN1; SMN2NPC1
SCHEMBL31070857 0.78 NPC1 (0.42) GAAMAPTRAB9AMEN1KMT2A
SCHEMBL6555412 0.78 NPC1 (0.42) GAAMAPTRAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023127507-A1 POWDERED PIGMENT COMPOSITION, METHOD FOR PRODUCING POWDERED PIGMENT COMPOSITION, RESIN COMPOSITION, AND MOLDED BODY DIC株式会社 2023-07-06 WO disclosed