Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.45 |
| ▸ | GRK6 | P43250 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23582810 | 0.80 | FFAR1 (0.50) | GAAFFAR1GRK6S1PR1KDM4E | |
| SCHEMBL17385281 | 0.80 | GAA (0.51) | GAAFFAR1S1PR1KDM4ENPC1 | |
| SCHEMBL8130190 | 0.79 | GAA (0.44) | GAANPC1RAB9ASMN1; SMN2LIPG | |
| SCHEMBL3087531 | 0.73 | MAOA (0.54) | GAACYP1A2LIPG | |
| SCHEMBL11331561 | 0.73 | KDM4E (0.51) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL30010034 | 0.72 | MAPT (0.43) | GAAGRK6KDM4ENPC1CYP1A2 | |
| SCHEMBL7114426 | 0.72 | GRK6 (0.59) | GAAGRK6KDM4ENPC1CYP1A2 | |
| SCHEMBL8626880 | 0.72 | PSMB8 (0.59) | KDM4ENPC1CYP1A2MAPTCYP2C19 | |
| SCHEMBL16515861 | 0.72 | CETP (0.42) | GRK6 | |
| SCHEMBL11339141 | 0.72 | RAB9A (0.47) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9677115-B2 | Enzyme substrates for visualizing acidic organelles | MARKER GENE TECHNOLOGIES, INC. (US) | 2017-06-13 | — | — | US | disclosed |
| US-20130252268-A1 | Enzyme substrates for visualizing acidic organelles | MARKER GENE TECHNOLOGIES, INC. (US) | 2013-09-26 | — | — | US | disclosed |
| US-8460862-B2 | Enzyme substrates for visualizing acidic organelles | Marker Gene Technologies (US) | 2013-06-11 | — | — | US | disclosed |
| US-20100233744-A1 | Enzyme substrates for visualizing acidic organelles | MARKER GENE TECHNOLOGIES, INC. | 2010-09-16 | — | — | US | disclosed |