Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22917014 | 0.82 | KMT2A (0.57) | KMT2ACYP2C19CYP2D6CYP2C9ALDH1A2 | |
| SCHEMBL861034 | 0.82 | KMT2A (0.57) | KMT2ACYP2C19CYP2D6CYP2C9ALDH1A2 | |
| SCHEMBL23188735 | 0.80 | ALDH1A1 (0.58) | KMT2ACYP2C19CYP2D6CYP2C9ALDH1A2 | |
| SCHEMBL23839910 | 0.80 | ALDH1A1 (0.58) | KMT2ACYP2C19CYP2D6CYP2C9ALDH1A2 | |
| SCHEMBL17777241 | 0.80 | ALDH1A1 (0.58) | KMT2ACYP2C19CYP2D6CYP2C9ALDH1A2 | |
| SCHEMBL18237463 | 0.79 | KMT2A (0.47) | KMT2ACYP2C19CYP2D6CYP2C9ALDH1A2 | |
| SCHEMBL18227194 | 0.78 | CYP2C19 (0.46) | KMT2ACYP2C19CYP2D6CYP2C9ALDH1A2 | |
| SCHEMBL12131751 | 0.77 | USP2 (0.55) | KMT2ACYP2C19CYP2D6CYP2C9ALDH1A2 | |
| SCHEMBL18227216 | 0.76 | KMT2A (0.45) | KMT2ACYP2C19CYP2D6CYP2C9ALDH1A2 | |
| SCHEMBL25801584 | 0.76 | SMN1; SMN2 (0.54) | KMT2AALDH1A1MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11696959-B2 | Nanoparticle-cell construct with platinum anti-cancer agent | CITY OF HOPE (US) | 2023-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11696959-B2 | Nanoparticle-cell construct with platinum anti-cancer agent | CD47, TP53, CD63 | KMT2A 1767/4885CYP2C19 4702/4885CYP2D6 4500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.