SCHEMBL25801694

SCHEMBL25801694

CCCCCCCCc1cc(CO)no1

nearest known ligand 0.64

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 1/20 0.64
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
PTGS2 P35354 2/20 0.38
KCNH2 Q12809 1/20 0.38
NOTUM Q6P988 2/20 0.38
ALDH1A1 P00352 1/20 0.38
RIPK1 Q13546 1/20 0.36
SPHK2 Q9NRA0 1/20 0.36
ELANE P08246 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1221911 0.98 PPARA (0.61) PPARANPC1RAB9ASMN1; SMN2PTGS2
SCHEMBL7505230 0.86 PPARA (0.64) PPARANPC1RAB9ASMN1; SMN2PTGS2
SCHEMBL7686496 0.86 PPARA (0.64) PPARANPC1RAB9ASMN1; SMN2PTGS2
SCHEMBL369102 0.85 PPARA (0.71) PPARANPC1RAB9ASMN1; SMN2PTGS2
SCHEMBL9210252 0.83 PPARA (0.46) PPARANOTUM
SCHEMBL25801691 0.83 PPARA (0.60) PPARANPC1RAB9ASMN1; SMN2PTGS2
SCHEMBL27880443 0.83 PPARA (0.60) PPARANPC1RAB9ASMN1; SMN2PTGS2
SCHEMBL3812770 0.80 PPARA (0.65) PPARANPC1RAB9ASMN1; SMN2PTGS2
SCHEMBL11933711 0.79 PPARA (0.55) PPARAPTGS2ALDH1A1ELANE
SCHEMBL15115449 0.79 PPARA (0.55) PPARAPTGS2ALDH1A1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES SITRYX THERAPEUTICS LIMITED (GB) 2023-07-13 US disclosed
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES SITRYX THERAPEUTICS LIMITED (GB) 2023-07-13 US disclosed
CN-115066418-A Carboxy derivatives with anti-inflammatory properties 西特瑞治疗有限公司 2022-09-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES CPA2, RO60, C5AR1 PPARA 1223/4885NPC1 4019/4885RAB9A 1795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.