⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21555973 | 0.84 | — | — | |
| SCHEMBL25938398 | 0.79 | — | — | |
| SCHEMBL20980228 | 0.78 | TP53 (0.36) | — | |
| SCHEMBL25941129 | 0.77 | — | — | |
| SCHEMBL23750552 | 0.77 | — | — | |
| SCHEMBL25843715 | 0.74 | — | — | |
| SCHEMBL18723300 | 0.74 | — | — | |
| SCHEMBL22644543 | 0.73 | — | — | |
| SCHEMBL18426813 | 0.70 | — | — | |
| SCHEMBL22384142 | 0.70 | TP53 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242586-A1 | RAS INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-08-03 | — | — | US | disclosed |
| US-20230212549-A1 | COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF | 3B PHARMACEUTICALS GMBH (DE) | 2023-07-06 | — | — | US | disclosed |