⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25941916 | 0.83 | — | — | |
| SCHEMBL25801704 | 0.77 | — | — | |
| SCHEMBL25939003 | 0.76 | — | — | |
| SCHEMBL21555973 | 0.76 | — | — | |
| SCHEMBL25843715 | 0.74 | — | — | |
| SCHEMBL25921868 | 0.71 | — | — | |
| SCHEMBL25939042 | 0.70 | — | — | |
| SCHEMBL25941937 | 0.70 | — | — | |
| SCHEMBL11890791 | 0.67 | USP2 (0.31) | — | |
| SCHEMBL25657495 | 0.67 | CHRM1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242586-A1 | RAS INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-08-03 | — | — | US | disclosed |