SCHEMBL25801817

SCHEMBL25801817

C1=CC(c2nc(-c3ccc(-c4ccc(N(c5ccccc5)c5ccc6sc7ccccc7c6c5)cc4)c4c3oc3ccccc34)nc3c2oc2ccccc23)=CCC1

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24256466 0.89 ALDH1A1 (0.37) KDM4EALDH1A1POLB
SCHEMBL25800859 0.86 ALDH1A1 (0.36) KDM4EALDH1A1POLB
SCHEMBL24256789 0.82 MAPT (0.38) KDM4EALDH1A1POLB
SCHEMBL26313092 0.81 MAPT (0.35) KDM4EALDH1A1POLB
SCHEMBL25802108 0.78 MEN1 (0.34)
SCHEMBL23686603 0.78 MAPT (0.35) KDM4EALDH1A1POLB
SCHEMBL26416627 0.77 ALDH1A1 (0.43) KDM4EALDH1A1POLB
SCHEMBL23686356 0.77 TSHR (0.35) KDM4EALDH1A1POLB
SCHEMBL24255863 0.76 ALDH1A1 (0.35) KDM4EALDH1A1POLB
SCHEMBL24255627 0.75 MAPT (0.34) KDM4EALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4201930-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING DEVICE LT Materials Co., Ltd. (KR) 2023-06-28 EP disclosed