SCHEMBL2580188

SCHEMBL2580188

CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccccc4)ccc3OCCCO)ccc21

nearest known ligand 0.80

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
RARG P13631 18/20 0.80
RARB P10826 10/20 0.80
RARA P10276 9/20 0.80
RXRA P19793 2/20 0.50
SLC6A9 P48067 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2581862 0.97 RARG (0.80) RARGRARBRARARXRASLC6A9
SCHEMBL344900 0.89 RARG (1.00) RARGRARBRARARXRA
SCHEMBL345553 0.88 RARG (0.76) RARGRARBRARARXRA
SCHEMBL27337606 0.87 RARG (0.84) RARGRARBRARARXRA
SCHEMBL345684 0.86 RARG (1.00) RARGRARBRARARXRA
SCHEMBL12152009 0.86 RARG (0.69) RARGRARBRARARXRA
SCHEMBL5845781 0.85 RARG (0.98) RARGRARBRARARXRA
SCHEMBL5846405 0.85 RARG (0.98) RARGRARBRARARXRA
SCHEMBL5846253 0.85 RARG (0.98) RARGRARBRARARXRA
SCHEMBL5845369 0.85 RARG (0.98) RARGRARBRARARXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8049034-B2 Biphenyl compound selective agonists of gamma RAR receptors GALDERMA RESEARCH & DEVELOPMENT (FR) 2011-11-01 US disclosed