Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 18/20 | 0.80 |
| ▸ | RARB | P10826 | 10/20 | 0.80 |
| ▸ | RARA | P10276 | 9/20 | 0.80 |
| ▸ | RXRA | P19793 | 2/20 | 0.49 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2580188 | 0.97 | RARG (0.80) | RARGRARBRARARXRASLC6A9 | |
| SCHEMBL345684 | 0.89 | RARG (1.00) | RARGRARBRARARXRA | |
| SCHEMBL5845781 | 0.88 | RARG (0.98) | RARGRARBRARARXRA | |
| SCHEMBL5845369 | 0.88 | RARG (0.98) | RARGRARBRARARXRA | |
| SCHEMBL5847036 | 0.88 | RARG (0.98) | RARGRARBRARARXRA | |
| SCHEMBL5846253 | 0.88 | RARG (0.98) | RARGRARBRARARXRA | |
| SCHEMBL5846405 | 0.88 | RARG (0.98) | RARGRARBRARARXRA | |
| SCHEMBL8525345 | 0.87 | RARG (0.65) | RARGRARBRARARXRA | |
| SCHEMBL8525048 | 0.87 | RARG (0.65) | RARGRARBRARARXRA | |
| SCHEMBL8527699 | 0.87 | RARG (0.65) | RARGRARBRARARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8049034-B2 | Biphenyl compound selective agonists of gamma RAR receptors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-11-01 | — | — | US | disclosed |