Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2924939 | 0.74 | CDK2 (0.39) | NTRK1 | |
| SCHEMBL27752731 | 0.73 | CDK2 (0.38) | NTRK1 | |
| SCHEMBL14688148 | 0.71 | NTRK1 (0.35) | NTRK1 | |
| SCHEMBL29031594 | 0.70 | ALDH1A1 (0.37) | NTRK1 | |
| SCHEMBL3750334 | 0.70 | MEN1 (0.40) | — | |
| SCHEMBL2849173 | 0.67 | KMT2A (0.50) | — | |
| SCHEMBL16778251 | 0.67 | CDK2 (0.32) | — | |
| SCHEMBL4434419 | 0.66 | CDK2 (0.40) | — | |
| SCHEMBL453104 | 0.65 | ELANE (0.46) | — | |
| SCHEMBL24768908 | 0.65 | CDK2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011137022-A1 | AZAINDOLES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2011-11-03 | — | — | WO | disclosed |