Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP28 | Q96RU2 | 1/20 | 0.40 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | FPR3 | P25089 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30563296 | 1.00 | USP28 (0.40) | USP28USP25DRD2DRD3FPR3 | |
| SCHEMBL30563385 | 0.77 | USP28 (0.59) | USP28USP25 | |
| SCHEMBL25804299 | 0.77 | USP28 (0.59) | USP28USP25 | |
| SCHEMBL25290787 | 0.77 | TP53 (0.34) | USP28USP25 | |
| SCHEMBL30563485 | 0.77 | TP53 (0.34) | USP28USP25 | |
| SCHEMBL25247189 | 0.73 | TP53 (0.33) | USP28USP25 | |
| SCHEMBL30563343 | 0.73 | TP53 (0.33) | USP28USP25 | |
| SCHEMBL25804293 | 0.72 | USP28 (0.56) | USP28USP25 | |
| SCHEMBL30563364 | 0.72 | USP28 (0.56) | USP28USP25 | |
| SCHEMBL30563276 | 0.70 | STING1 (0.43) | USP28USP25 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |